Leadership

Leading inclusively with integrity and vision

Aimee Kao, MD, PhD

Aimee Kao, MD, PhD

Professor, Neurology
UCSF Profile | Lab Website

Core A Lead; Project 1 Lead

Dr. Kao is a neuroscientist and physician interested in understanding the pathophysiological mechanisms underlying neurodegenerative disorders, focusing on how aging and disease impact lysosome function and protein homeostasis. 

 


 

Jennifer Yokoyama, PhD

Jennifer Yokoyama, PhD

Associate Professor, Neurology
UCSF Profile | Lab Website

Core A Co-Lead; Core C Lead

Dr. Yokoyama is a geneticist and neuroscientist who is interested in understanding how variation across the genome contributes to changes in structure and function as the brain ages.

 


 

David Agard, PhD

David Agard, PhD

Professor, Biochemistry and Biophysics
UCSF Profile | Lab Website

Core B Lead, Project 1 Co-Lead

Dr. Agard is a structural biophysicist focused on elucidating the mechanisms of assisted folding by the Hsp90 molecular chaperone system and the mechanisms of microtubule nucleation.

 


 

Efstathios Gennatas, PhD

Efstathios Gennatas, PhD

Assistant Professor, Epidemiology and Biostatistics
UCSF Profile | Lab Website

Core C Co-Lead

Dr. Gennatas is a neuroscientist focused on the development of advanced machine learning methods to address the challenges inherent in basic biomedical research and clinical predictive modeling.

 


 

Celeste Karch, PhD

Celeste Karch, PhD

Associate Professor, Psychiatry
WUSTL Profile | Lab Website

Project 2 Lead

Dr. Karch is a leader in neurogenomics and stem cell models of tauopathy, focused on understanding the molecular drivers of Alzheimer’s disease, Frontotemporal dementia, and other neurodegenerative diseases.