Aimee Kao, MD, PhD
Professor, Neurology
UCSF Profile | Lab Website
Core A Lead; Project 1 Lead
Dr. Kao is a neuroscientist and physician interested in understanding the pathophysiological mechanisms underlying neurodegenerative disorders, focusing on how aging and disease impact lysosome function and protein homeostasis.
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Jennifer Yokoyama, PhD
Associate Professor, Neurology
UCSF Profile | Lab Website
Core A Co-Lead; Core C Lead
Dr. Yokoyama is a geneticist and neuroscientist who is interested in understanding how variation across the genome contributes to changes in structure and function as the brain ages.
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David Agard, PhD
Professor, Biochemistry and Biophysics
UCSF Profile | Lab Website
Core B Lead, Project 1 Co-Lead
Dr. Agard is a structural biophysicist focused on elucidating the mechanisms of assisted folding by the Hsp90 molecular chaperone system and the mechanisms of microtubule nucleation.
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Efstathios Gennatas, PhD
Assistant Professor, Epidemiology and Biostatistics
UCSF Profile | Lab Website
Core C Co-Lead
Dr. Gennatas is a neuroscientist focused on the development of advanced machine learning methods to address the challenges inherent in basic biomedical research and clinical predictive modeling.
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Celeste Karch, PhD
Associate Professor, Psychiatry
WUSTL Profile | Lab Website
Project 2 Lead
Dr. Karch is a leader in neurogenomics and stem cell models of tauopathy, focused on understanding the molecular drivers of Alzheimer’s disease, Frontotemporal dementia, and other neurodegenerative diseases.
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